Overview

  • Product name

    7-epi-Cephalomannine, antineoplastic agent
  • Description

    Paclitaxel analog. Putative antineoplastic agent.
  • Biological description

    Paclitaxel (ab120143) analog. Putative antineoplastic agent. Cephalomannine (ab142589) derivative. Induces apoptosis.
  • Purity

    > 98%
  • CAS Number

    150547-36-7
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    831.90
  • Molecular formula

    C45H53NO14
  • PubChem identifier

    71314642
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC=C(C)C(=O)NC(C1=CC=CC=C1)C(C(=O)OC2CC3(C(C4C(C(CC5C4(CO5)OC(=O)C)O)(C(=O)C(C(=C2C)C3(C)C)OC(=O)C)C)OC(=O)C6=CC=CC=C6)O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Gao F  et al. Synthesis, isolation, stereostructure and cytotoxicity of paclitaxel analogs from cephalomannine. Fitoterapia 90:79-84 (2013). Read more (PubMed: 23876369) »
  • Zhang YY  et al. C-7 configuration as one of determinants in taxanes metabolism by human cytochrome P450 enzymes. Xenobiotica 39:903-14 (2009). Read more (PubMed: 19795923) »
  • Pandey RC  et al. Synthesis and separation of potential anticancer active dihalocephalomannine diastereomers from extracts of Taxus yunnanensis. J Nat Prod 61:57-63 (1998). Read more (PubMed: 9461653) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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