Overview

  • Product name

    7,8-Dihydroxyflavone (7,8-DHF), TrkB receptor agonist. Flavonoid.
  • Description

    Selective TrkB receptor agonist. Flavonoid.
  • Biological description

    Selective TrkB receptor agonist. Flavonoid. Enhances synaptic plasticity in vivo and in vitro. Blood-brain barrier permeable.
  • Purity

    > 99%
  • CAS Number

    38183-03-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Devi L & Ohno M 7,8-dihydroxyflavone, a small-molecule TrkB agonist, reverses memory deficits and BACE1 elevation in a mouse model of Alzheimer's disease. Neuropsychopharmacology 37:434-44 (2012). Read more (PubMed: 21900882) »
  • Zeng Y  et al. 7,8-dihydroxyflavone rescues spatial memory and synaptic plasticity in cognitively impaired aged rats. J Neurochem 122:800-11 (2012). Read more (PubMed: 22694088) »
  • Jang SW  et al. A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone. Proc Natl Acad Sci U S A 107:2687-92 (2010). Read more (PubMed: 20133810) »
See 1 Publication for this product

Customer reviews and Q&As

Answer

Some products may be difficult to solubilise it may be that rapid stirring, warming in a water bath, or sonication of the solution may help.

Read More

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up