Product name7alpha-Hydroxycholesterol, Bile acid precursor
DescriptionBile acid precursor. Displays pro-inflammatory activity.
- 7 alpha-hydroxycholesterol
Bile acid precursor produced by cholesterol 7 alpha-hydroxylase. Induces inflammation by enhancing production of chemokine (C-C motif) ligand 2. Elicits TLR6-Mediated Expression of IL-23 in Monocytic Cells.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Kim SM et al. 7a-Hydroxycholesterol induces inflammation by enhancing production of chemokine (C-C motif) ligand 2. Biochem Biophys Res Commun 467:879-84 (2015). Read more (PubMed: 26474699) »
- Seo HC et al. 7a-Hydroxycholesterol Elicits TLR6-Mediated Expression of IL-23 in Monocytic Cells. Biomol Ther (Seoul) 23:84-9 (2015). Read more (PubMed: 25593648) »
- Hahn C et al. Serum concentration of 7 alpha-hydroxycholesterol as an indicator of bile acid synthesis in humans. J Lipid Res 36:2059-66 (1995). Read more (PubMed: 8558093) »