Key features and details
- Selective A2A receptor antagonist. MAO-B inhibitor.
- CAS Number: 147700-11-6
- Purity: > 98%
- Soluble in DMSO to 25 mM (with heating)
- Form / State: Solid
- Source: Synthetic
Product name8-(3-Chlorostyryl)caffeine, A2A receptor antagonist. MAO-B inhibitor.
DescriptionSelective A2A receptor antagonist. MAO-B inhibitor.
Selective A2A receptor antagonist and MAO-B (monoamine oxidase B) inhibitor (Ki values are 54 and 100 nM, respectively). Affords strong neuroprotection against 6-OHDA-induced neurotoxicity in vitro and is neuroprotective in Parkinson's disease models.
Storage instructionsStore at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
Solubility overviewSoluble in DMSO to 25 mM (with heating)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Epigenetics and Nuclear Signaling
- Domain Families
- HLH / Leucine Zipper
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120442 has not yet been referenced specifically in any publications.