Overview

  • Product name
    8-Br-cGMP (8-Bromo-cGMP), PKG activator
  • Description
    Cell permeable cGMP analog. PKG activator.
  • Biological description
    Cell permeable cGMP analog. PKG activator. Increases Ca2+ levels and active in vivo.
  • Purity
    > 95%

Properties

Associated products

References

This product has been referenced in:
  • Cuppoletti J  et al. Contrasting effects of linaclotide and lubiprostone on restitution of epithelial cell barrier properties and cellular homeostasis after exposure to cell stressors. BMC Pharmacol 12:3 (2012). Read more (PubMed: 22553939) »
  • Porter M  et al. Convergence of Ca2+-desensitizing mechanisms activated by forskolin and phenylephrine pretreatment, but not 8-bromo-cGMP. Am J Physiol Cell Physiol 290:C1552-9 (2006). Read more (PubMed: 16421202) »
  • Rashatwar SS  et al. Effects of 8-bromo-cGMP on Ca2+ levels in vascular smooth muscle cells: possible regulation of Ca2+-ATPase by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A 84:5685-9 (1987). Read more (PubMed: 3039502) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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