Product name8-Hydroxyguanosine 5'-triphosphate triethylammonium salt, oxidized ribonucleotide
DescriptionOxidized ribonucleotide that induces mutations in cDNA, suggesting disturbance of genetic information during transcription and/or reverse transcription.
- 7,8-Dihydro-8-oxoguanosine 5’-(Tetrahydrogen Triphosphate) Triethylammonium Salt
- 8-Ketoguanosine 5’-Triphosphate Bis(triethylammonium) Triethylammonium Salt
- 8-OH-GTP Di-TEA Triethylammonium Salt
Oxidized ribonucleotide that induces mutations in cDNA, suggesting disturbance of genetic information during transcription and/or reverse transcription. Potential antiviral drug that cause mutations in genomic RNA.
Chemical name7,8-Dihydro-8-oxoguanosine 5'-triphosphate triethylammonium salt
Storage instructionsStore at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Kamiya H et al. Incorporation of 8-hydroxyguanosine (8-oxo-7,8-dihydroguanosine) 5'-triphosphate by bacterial and human RNA polymerases. Free Radic Biol Med 46:1703-7 (2009). Read more (PubMed: 19362141) »
- Kamiya H et al. Effects of 8-hydroxy-GTP and 2-hydroxy-ATP on in vitro transcription. Free Radic Biol Med 43:837-43 (2007). Read more (PubMed: 17664147) »
- Kamiya H et al. Mutagenic properties of oxidized GTP and ATP in in vitro transcription-reverse transcription. Nucleic Acids Symp Ser (Oxf) N/A:99-100 (2006). Read more (PubMed: 17150836) »