8-Hydroxyquinoline (8HQ), RNA synthesis inhibitor and ion chelator (ab141198)

Overview

  • Product name

    8-Hydroxyquinoline (8HQ), RNA synthesis inhibitor and ion chelator
  • Description

    RNA synthesis inhibitor and ion chelator
  • Alternative names

    • 8HQ
  • Biological description

    RNA synthesis inhibitor. Displays antimicrobial activity and also shows chelating properties. Active in vivo.
  • Purity

    > 99%
  • CAS Number

    148-24-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Darby CM & Nathan CF Killing of non-replicating Mycobacterium tuberculosis by 8-hydroxyquinoline. J Antimicrob Chemother 65:1424-7 (2010). Read more (PubMed: 20435781) »
  • Fraser RS & Creanor J The mechanism of inhibition of ribonucleic acid synthesis by 8-hydroxyquinoline and the antibiotic lomofungin. Biochem J 147:401-10 (1975). Read more (PubMed: 810137) »
  • GERSHON H & PARMEGIANI R Antimicrobial activity of 8-quinolinol, its salts with salicylic acid and 3-hydroxy-2-naphthoic acid, and the respective copper (II) chelates in liquid culture. Appl Microbiol 11:62-5 (1963). Read more (PubMed: 13960592) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab141198.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up