Precursor molecule to several chemotherapeutic agents. Catabolic product of carbamazepine (ab141785) metabolite. Used as a fluorescent tag for antibody catalysis.
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Soluble in DMSO
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Mathieu O et al. Presence and ex vivo formation of acridone in blood of patients routinely treated with carbamazepine: exploration of the 9-acridinecarboxaldehyde pathway. Xenobiotica41:91-100 (2011).
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Reymond JL et al. A general assay for antibody catalysis using acridone as a fluorescent tag. Proc Natl Acad Sci U S A93:4251-6 (1996).
Read more (PubMed: 8633050) »