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Amino Acid Sequence
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ab204881 (Acetyl Coenzyme A Carboxylase peptide) can be utilized as a substrate for the following active protein kinases:
ab184883 (Active human AMPK alpha 1 + AMPK beta 2 +AMPK gamma 2 full length protein)
ab79803 (Active human AMPK alpha1 + AMPK beta1 + AMPK gamma1 full length protein)
ab126911 (Active human PRKAA2 + PRKAB2 + PRKAG1 full length protein)
ab126916 (Active human AMPK alpha 2 full length protein)
ab184885 (Active human AMPK alpha 1 + AMPK beta 2 + AMPK gamma 3 full length protein)
ab185258 (Active human AMPK alpha 2 + beta 1 + gamma 2 full length protein)
Concentration information loading...
Stability and Storage
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.
Dilute peptide in 20mM Tris-HCl, pH 7.5 solution to a final concentration of 1 mg/ml. For optimal storage, aliquot diluted product into smaller quantities and store at recommended temperature.
Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
Expressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver.
Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.
Involvement in disease
Acetyl-CoA carboxylase 1 deficiency
Contains 1 ATP-grasp domain.
Contains 1 biotin carboxylation domain.
Contains 1 biotinyl-binding domain.
Contains 1 carboxyltransferase domain.
Phosphorylation on Ser-1263 is required for interaction with BRCA1.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"