Anti-Aprotinin antibody [35] (ab82110)
Key features and details
- Mouse monoclonal [35] to Aprotinin
- Suitable for: Indirect ELISA, WB
- Reacts with: Cow
- Isotype: IgG1
Overview
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Product name
Anti-Aprotinin antibody [35] -
Description
Mouse monoclonal [35] to Aprotinin -
Host species
Mouse -
Tested applications
Suitable for: Indirect ELISA, WBmore details -
Species reactivity
Reacts with: Cow -
Immunogen
Full length native protein (purified) corresponding to Cow Aprotinin. Aprotinin from bovine lung adsorbed onto aluminum hydroxide gel
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Positive control
- Bovine lung
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.097% Sodium azide
Constituents: 0.0268% PBS, 2.9% Sodium chloride -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
35 -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab82110 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Indirect ELISA |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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Notes |
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Indirect ELISA
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
Target
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Relevance
Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. It is present in blood and in most tissues, with a high concentration in lung, inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, Aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins. Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids arranged in a single polypeptide chain, cross-linked by three disulfide bridges. -
Cellular localization
Secreted -
Database links
- Entrez Gene: 404172 Cow
- SwissProt: P00974 Cow
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Alternative names
- Basic protease inhibitor antibody
- BPI antibody
- BPTI antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab82110 has been referenced in 1 publication.
- Zlokovic BV et al. Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer's amyloid ß-peptide elimination from the brain. J Neurochem 115:1077-89 (2010). WB, ELISA . PubMed: 20854368