BAPTA, extracellular calcium chelator (ab144924)
Key features and details
- Selective, membrane impermeable extracellular calcium chelator
- CAS Number: 85233-19-8
- Soluble in DMSO to 25 mM
- Form / State: Powder
- Source: Synthetic
Overview
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Product name
BAPTA, extracellular calcium chelator -
Description
Selective, membrane impermeable extracellular calcium chelator -
CAS Number
85233-19-8 -
Chemical structure
Properties
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Chemical name
2-[2-[2-[2-[Bis(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)anilino]acetic acid -
Molecular weight
476.43 -
Molecular formula
C22H24N2O10 -
PubChem identifier
104751 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC=C(C(=C1)N(CC(=O)O)CC(=O)O)OCCOC2=CC=CC=C2N(CC(=O)O)CC(=O)O -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab144924 has been referenced in 2 publications.
- Lautenschläger J et al. Intramitochondrial proteostasis is directly coupled to a-synuclein and amyloid ß1-42 pathologies. J Biol Chem 295:10138-10152 (2020). PubMed: 32385113
- Qiang L et al. Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis. Autophagy 13:2086-2103 (2017). PubMed: 28933598