Anti-Basal Bodies of Cillia antibody [LhS28] (ab14373)
Key features and details
- Mouse monoclonal [LhS28] to Basal Bodies of Cillia
- Suitable for: IHC-P, IHC-Fr, IP
- Reacts with: Human
- Isotype: IgG1
Overview
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Product name
Anti-Basal Bodies of Cillia antibody [LhS28] -
Description
Mouse monoclonal [LhS28] to Basal Bodies of Cillia -
Host species
Mouse -
Specificity
This antibody recognises the basal bodies of cillia in all cilliated cells. -
Tested applications
Suitable for: IHC-P, IHC-Fr, IPmore details -
Species reactivity
Reacts with: Human -
Immunogen
Tissue, cells or virus corresponding to Human Basal Bodies of Cillia. Cytoskeletal preparation of the BHK a21 cell line expressing cillia basal bodies (Human).
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
LhS28 -
Myeloma
Sp2/0 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab14373 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P | (1) |
Use at an assay dependent concentration.
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IHC-Fr |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
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Notes |
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IHC-P
Use at an assay dependent concentration. |
IHC-Fr
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
Target
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Relevance
Flagella and cillia both project from the cell surface and beat in distinctive patterns. Flagella are whiplike tails that propel many free-living cells, such as sperm, through fluid environments. Cilia are shorter and usually more profuse than flagella. In both flagella and cilia, nine pairs of microtubules ring two central microtubules. This arrangement is called a "9 + 2 array." A system of spokes and links holds the arrangement together. Microtubules of a flagellum or cilium arise from centrioles, which remain at the base of the completed structure as a basal body. These are sites of dense material that generate large numbers of microtubules.
Datasheets and documents
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SDS download
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Datasheet download
References (6)
ab14373 has been referenced in 6 publications.
- Wong AP et al. Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells. Nat Protoc 10:363-81 (2015). PubMed: 25654755
- Pier B et al. Effect of cigarette smoking on human oviductal ciliation and ciliogenesis. Fertil Steril 99:199-205 (2013). PubMed: 23009827
- Auersperg N The origin of ovarian carcinomas: a unifying hypothesis. Int J Gynecol Pathol 30:12-21 (2011). IHC-P ; Human . PubMed: 21131839
- Comer MT et al. Application of a marker of ciliated epithelial cells to gynaecological pathology. J Clin Pathol 52:355-7 (1999). PubMed: 10560355
- Comer MT et al. Expression of an antigen associated with basal bodies of human ciliated epithelial cells. Histochem J 31:39-43 (1999). PubMed: 10405821
- Comer MT et al. Induction of a differentiated ciliated cell phenotype in primary cultures of Fallopian tube epithelium. Hum Reprod 13:3114-20 (1998). PubMed: 9853867