Anti-C Reactive Protein antibody [C2] (ab136176)
Key features and details
- Mouse monoclonal [C2] to C Reactive Protein
- Suitable for: Competitive ELISA, ELISA, IHC-P, Sandwich ELISA
- Reacts with: Human
- Isotype: IgG1
Overview
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Product name
Anti-C Reactive Protein antibody [C2]
See all C Reactive Protein primary antibodies -
Description
Mouse monoclonal [C2] to C Reactive Protein -
Host species
Mouse -
Tested applications
Suitable for: Competitive ELISA, ELISA, IHC-P, Sandwich ELISAmore details -
Species reactivity
Reacts with: Human -
Immunogen
Human C Reactive Protein, derived from pleural/ascetic fluid or plasma.
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General notes
This product was changed from ascites to tissue culture supernatant on 17th October 2017 and product received after this date will be from tissue culture supernatant.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
C2 -
Myeloma
Sp2/0 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Conjugation kits
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Isotype control
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sELISA pair antibody
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab136176 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Competitive ELISA |
Use at an assay dependent concentration.
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ELISA |
Use at an assay dependent concentration.
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IHC-P |
Use at an assay dependent concentration.
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Sandwich ELISA |
Use at an assay dependent concentration. Can be paired for Sandwich ELISA with HRP Mouse monoclonal [C6] to C Reactive Protein (ab24462) and Mouse monoclonal [C6] to C Reactive Protein (ab8278).
Recommended pairs for sandwich immunoassay(capture - detection):C2 - C6C5 - C6C7 - C6. |
Notes |
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Competitive ELISA
Use at an assay dependent concentration. |
ELISA
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
Sandwich ELISA
Use at an assay dependent concentration. Can be paired for Sandwich ELISA with HRP Mouse monoclonal [C6] to C Reactive Protein (ab24462) and Mouse monoclonal [C6] to C Reactive Protein (ab8278). Recommended pairs for sandwich immunoassay(capture - detection):C2 - C6C5 - C6C7 - C6. |
Target
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Function
Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. -
Tissue specificity
Found in plasma. -
Sequence similarities
Belongs to the pentaxin family.
Contains 1 pentaxin domain. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 1401 Human
- Omim: 123260 Human
- SwissProt: P02741 Human
- Unigene: 709456 Human
- Unigene: 76452 Human
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Alternative names
- Pentraxin 1, short antibody
- C reactive protein antibody
- C reactive protein pentraxin related antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab136176 has been referenced in 3 publications.
- He G et al. Mitigating hook effect in one-step quantitative sandwich lateral flow assay by timed conjugate release. Talanta 240:123157 (2022). PubMed: 34968809
- Zong C et al. Metal-enhanced chemiluminescence detection of C-reaction protein based on silver nanoparticle hybrid probes. Talanta 199:164-169 (2019). PubMed: 30952241
- Jiang T et al. Scolopendra subspinipes mutilans L. Koch Ameliorates Rheumatic Heart Disease by Affecting Relative Percentages of CD4+CD25+FoxP3 Treg and CD4+IL17 T Cells. Evid Based Complement Alternat Med 2019:4674190 (2019). PubMed: 31379962