Anti-Betatrophin antibody - N-terminal (ab180915)
Key features and details
- Rabbit polyclonal to Betatrophin - N-terminal
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-Betatrophin antibody - N-terminal
See all Betatrophin primary antibodies -
Description
Rabbit polyclonal to Betatrophin - N-terminal -
Host species
Rabbit -
Specificity
At least three isoforms of Betatrophin are known to exist (NP_061157, AAF76204 / EAW84186, EAW84185). ab180915 will detect the two largest isoforms of Betatrophin.
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Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide corresponding to Human Betatrophin (N terminal). 16 amino acids long. NP_061157
Database link: Q6UXH0 -
Positive control
- Rat liver tissue lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab180915 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).
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IHC-P |
Use a concentration of 5 µg/ml.
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Notes |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa). |
IHC-P
Use a concentration of 5 µg/ml. |
Target
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Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 55908 Human
- SwissProt: Q6UXH0 Human
- Unigene: 534467 Human
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Alternative names
- Angiopoietin-like protein 8 antibody
- ANGPTL8 antibody
- betatrophin antibody
see all
Images
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Lane 1 : Anti-Betatrophin antibody - N-terminal (ab180915) at 1 µg/ml
Lane 2 : Anti-Betatrophin antibody - N-terminal (ab180915) at 2 µg/ml
All lanes : Rat liver tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 22 kDa -
Immunofluorescence of Betatrophin in rat liver tissue with ab180915 at 20 μg/mL.
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Immunohistochemistry of Betatrophin in rat liver tissue with ab180915 at 5 μg/mL.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab180915 has been referenced in 2 publications.
- Zhang D et al. Recombinant betatrophin (Angptl-8/lipasin) ameliorates streptozotocin-induced hyperglycemia and ß-cell destruction in neonatal rats. Mol Med Rep 20:4523-4532 (2019). PubMed: 31702044
- Wang R et al. Neuropeptide Y-Positive Neurons in the Dorsomedial Hypothalamus Are Involved in the Anorexic Effect of Angptl8. Front Mol Neurosci 11:451 (2018). PubMed: 30618603