Anti-CCR7 antibody [4B12] - Low endotoxin, Azide free (ab185745)
Key features and details
- Rat monoclonal [4B12] to CCR7 - Low endotoxin, Azide free
- Suitable for: Flow Cyt
- Reacts with: Rat
- Isotype: IgG2a
Related conjugates and formulations
Overview
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Product name
Anti-CCR7 antibody [4B12] - Low endotoxin, Azide free
See all CCR7 primary antibodies -
Description
Rat monoclonal [4B12] to CCR7 - Low endotoxin, Azide free -
Host species
Rat -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Rat -
Immunogen
Tissue, cells or virus corresponding to CCR7.
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Positive control
- Mouse splenocytes and thymocytes; rat RBL cells expressing mouse CCR7.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
1XPBS W/O NaN3 -
Carrier free
Yes -
Concentration information loading...
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Purity
Affinity purified -
Purification notes
Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by the LAL assay. -
Clonality
Monoclonal -
Clone number
4B12 -
Isotype
IgG2a -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab185745 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Flow Cyt |
Use 1µg for 105-8 cells.
ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Notes |
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Flow Cyt
Use 1µg for 105-8 cells. ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Target
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Function
Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. -
Tissue specificity
Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
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Alternative names
- BLR 2 antibody
- BLR2 antibody
- C C chemokine receptor type 7 antibody
see all
Images
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Flow cytometry analysis of rat RBL cells co-expressing mouse CCR7 and a GFP protein from an IRES-containing retrovirus. These cells were stained with either rat IgG2a kappa Isotype Control PE (left) or 1 µg of ab185745 (right) followed by F(ab')2 anti-rat IgG PE. GFP expression is shown in FL1 on the X-axis. Total viable cells were used for analysis.
Datasheets and documents
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Datasheet download
References (0)
ab185745 has not yet been referenced specifically in any publications.