Anti-CD5 antibody [C5/473 + CD5/54/F6] (ab200697)
Key features and details
- Mouse monoclonal [C5/473 + CD5/54/F6] to CD5
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
Overview
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Product name
Anti-CD5 antibody [C5/473 + CD5/54/F6]
See all CD5 primary antibodies -
Description
Mouse monoclonal [C5/473 + CD5/54/F6] to CD5 -
Host species
Mouse -
Specificity
ab200697 does not react with granulocytes or monocytes. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Rat, Rabbit, Cow -
Immunogen
Recombinant fragment corresponding to Human CD5. Clone C5/473
Database link: P06127 -
Positive control
- IHC-P: Human tonsil tissue.
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General notes
Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-).
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Please note that this antibody is an oligoclonal antibody. It is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies have not only the specificity and batch-to-batch consistency of a monoclonal antibody, but also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.05% BSA -
Concentration information loading...
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Purity
Protein A/G purified -
Purification notes
ab200697 was purified from Bioreactor Concentrate. -
Clonality
Monoclonal -
Clone number
C5/473 + CD5/54/F6 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab200697 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
Use a concentration of 1 - 2 µg/ml.
Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA, pH 7.5-8.5, for 45 min at 95°C followed by cooling at RT for 20 minutes. |
Notes |
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IHC-P
Use a concentration of 1 - 2 µg/ml. Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA, pH 7.5-8.5, for 45 min at 95°C followed by cooling at RT for 20 minutes. |
Target
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Function
May act as a receptor in regulating T-cell proliferation. CD5 interacts with CD72/LYB-2. -
Sequence similarities
Contains 3 SRCR domains. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 280745 Cow
- Entrez Gene: 921 Human
- Entrez Gene: 100008958 Rabbit
- Entrez Gene: 54236 Rat
- Omim: 153340 Human
- SwissProt: P19238 Cow
- SwissProt: P06127 Human
- SwissProt: P51882 Rat
see all -
Alternative names
- CD 5 antibody
- CD5 antibody
- CD5 antigen (p56 62) antibody
see all
Images
Datasheets and documents
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Datasheet download
References (0)
ab200697 has not yet been referenced specifically in any publications.