Anti-CEBP Alpha/CEBPA antibody (ab15048)
Key features and details
- Rabbit polyclonal to CEBP Alpha/CEBPA
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
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Overview
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Product name
Anti-CEBP Alpha/CEBPA antibody
See all CEBP Alpha/CEBPA primary antibodies -
Description
Rabbit polyclonal to CEBP Alpha/CEBPA -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Recombinant fragment corresponding to Rat CEBP Alpha/CEBPA.
Database link: NM_012524 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 99% PBS, 0.1% BSA -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab15048 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (2) |
Use a concentration of 2 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 30,43 kDa).
Detects bands of approximately 30 kDa and 43 kDa representing CEBP alpha in mouse 3T3-L1 cells. |
Notes |
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WB
Use a concentration of 2 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 30,43 kDa). Detects bands of approximately 30 kDa and 43 kDa representing CEBP alpha in mouse 3T3-L1 cells. |
Target
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Function
C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. -
Sequence similarities
Belongs to the bZIP family. C/EBP subfamily.
Contains 1 bZIP domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 12606 Mouse
- SwissProt: P53566 Mouse
- Unigene: 349667 Mouse
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Alternative names
- Apoptotic cysteine protease antibody
- Apoptotic protease Mch 5 antibody
- C/EBP alpha antibody
see all
Images
Datasheets and documents
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Datasheet download
References (8)
ab15048 has been referenced in 8 publications.
- Huang Y et al. Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia. Cancer Cell 35:677-691.e10 (2019). PubMed: 30991027
- Fatima LA et al. Estradiol stimulates adipogenesis and Slc2a4/GLUT4 expression via ESR1-mediated activation of CEBPA. Mol Cell Endocrinol 498:110447 (2019). PubMed: 31100494
- Jung M et al. Inhibiting casein kinase 2 overcomes paclitaxel resistance in gastric cancer. Gastric Cancer 22:1153-1163 (2019). PubMed: 31098863
- Lee D et al. HMGB2 is a novel adipogenic factor that regulates ectopic fat infiltration in skeletal muscles. Sci Rep 8:9601 (2018). PubMed: 29942000
- Jang MK et al. Histone H3K9 Demethylase JMJD2B Activates Adipogenesis by Regulating H3K9 Methylation on PPAR? and C/EBPa during Adipogenesis. PLoS One 12:e0168185 (2017). WB . PubMed: 28060835
- Ma Y et al. Highly efficient genome editing of human hematopoietic stem cells via a nano-silicon-blade delivery approach. Integr Biol (Camb) 9:548-554 (2017). PubMed: 28513735
- Ptasinska A et al. Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal. Cell Rep 8:1974-1988 (2014). WB . PubMed: 25242324
- Khanna-Gupta A et al. Up-regulation of Translation Eukaryotic Initiation Factor 4E in Nucleophosmin 1 Haploinsufficient Cells Results in Changes in CCAAT Enhancer-binding Protein a Activity: IMPLICATIONS IN MYELODYSPLASTIC SYNDROME AND ACUTE MYELOID LEUKEMIA. J Biol Chem 287:32728-37 (2012). WB . PubMed: 22851180