Anti-CMKLR1 antibody (ab64881)
Key features and details
- Rabbit polyclonal to CMKLR1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CMKLR1 antibody
See all CMKLR1 primary antibodies -
Description
Rabbit polyclonal to CMKLR1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide from an internal sequence of Human CMKLR1.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab64881 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/500 - 1/1000. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa).
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Notes |
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WB
1/500 - 1/1000. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa). |
Target
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Function
Orphan receptor. Could be a chemotactic peptide receptor. May have a function in bone metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2). -
Tissue specificity
Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Developmental stage
Expressed during bone development. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 1240 Human
- Omim: 602351 Human
- SwissProt: Q99788 Human
- Unigene: 197143 Human
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Alternative names
- CHEMERINR antibody
- Chemokine like receptor 1 antibody
- Chemokine-like receptor 1 antibody
see all
Images
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All lanes : Anti-CMKLR1 antibody (ab64881) at 1/500 dilution
Lane 1 : extracts from HepG2 cells (5-30µg total protein).
Lane 2 : extracts from HeLa cells (5-30µg total protein).
Lane 3 : extracts from 293 cells (5-30µg total protein).
Lane 4 : extracts from 293 cells (5-30µg total protein) and 5-10µg of the immunising peptide.
Predicted band size: 43 kDa
Observed band size: 43 kDa
Additional bands at: 26 kDa, 34 kDa. We are unsure as to the identity of these extra bands.
Datasheets and documents
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SDS download
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Datasheet download
References (14)
ab64881 has been referenced in 14 publications.
- Schmitt M et al. Anti-Tumoral Effect of Chemerin on Ovarian Cancer Cell Lines Mediated by Activation of Interferon Alpha Response. Cancers (Basel) 14:N/A (2022). PubMed: 36077645
- Wisanwattana W et al. Inhibition of Phosphodiesterase 5 Promotes the Aromatase-Mediated Estrogen Biosynthesis in Osteoblastic Cells by Activation of cGMP/PKG/SHP2 Pathway. Front Endocrinol (Lausanne) 12:636784 (2021). PubMed: 33776932
- Yadav P et al. Selective Activation of MST1/2 Kinases by Retinoid Agonist Adapalene Abrogates AURKA-Regulated Septic Arthritis. J Immunol 206:2888-2899 (2021). PubMed: 34031150
- Zhang H et al. Alpha-lipoic acid could attenuate the effect of chemerin-induced diabetic nephropathy progression. Iran J Basic Med Sci 24:1107-1116 (2021). PubMed: 34804428
- Brzoskwinia M et al. Flutamide Alters the Expression of Chemerin, Apelin, and Vaspin and Their Respective Receptors in the Testes of Adult Rats. Int J Mol Sci 21:N/A (2020). PubMed: 32580404