Anti-CRF1/CRHR1 antibody (ab150561)
Key features and details
- Rabbit polyclonal to CRF1/CRHR1
- Suitable for: IHC-P
- Reacts with: Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-CRF1/CRHR1 antibody
See all CRF1/CRHR1 primary antibodies -
Description
Rabbit polyclonal to CRF1/CRHR1 -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Rat, Human
Predicted to work with: Mouse, Horse, Hamster, Cow, Dog, Pig, Bird, Lizard, Monkey, Zebrafish, Gorilla, Common marmoset, Elephant -
Immunogen
Synthetic peptide corresponding to Human CRF1/CRHR1 (N terminal). Synthetic peptide, corresponding to 18 amino acids from the N-terminal extracellular domain of Human CRF1/CRHR1.
Database link: P34998 -
Positive control
- Human brain (neurons and glia) tissue; Rat hypothalamus tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab150561 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P | (1) |
Use a concentration of 21 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 21 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. -
Tissue specificity
Predominantly expressed in the cerebellum, pituitary, cerebral cortex and olfactory lobe. -
Sequence similarities
Belongs to the G-protein coupled receptor 2 family. -
Post-translational
modificationsC-terminal Ser or Thr residues may be phosphorylated. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 281716 Cow
- Entrez Gene: 100065598 Horse
- Entrez Gene: 1394 Human
- Entrez Gene: 12921 Mouse
- Entrez Gene: 397426 Pig
- Entrez Gene: 58959 Rat
- Entrez Gene: 567940 Zebrafish
- Omim: 122561 Human
see all -
Alternative names
- corticotropin releasing factor receptor antibody
- Corticotropin releasing factor type 1 receptor antibody
- corticotropin releasing hormone receptor 1 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab150561 has not yet been referenced specifically in any publications.