Key features and details
- Rabbit polyclonal to CRMP4
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-CRMP4 antibody
See all CRMP4 primary antibodies
DescriptionRabbit polyclonal to CRMP4
SpecificityNo cross reactivity was detected with CRMP1, CRMP2, CRMP3 or CRMP5.
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
A 15 residue synthetic peptide derived from C-terminal domain of human collapsing-response mediator (Type 4).
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferConstituent: Whole serum
Concentration information loading...
Our Abpromise guarantee covers the use of ab36204 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/2000. Predicted molecular weight: 65 kDa.|
FunctionNecessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
Tissue specificityMainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord.
Sequence similaritiesBelongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
modificationsPhosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3.
Cellular localizationCytoplasm. Cell projection > growth cone. Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
- Information by UniProt
- Collapsin response mediator protein 4 antibody
- Collapsin response mediator protein 4 long antibody
- CRMP 4 antibody
All lanes : Anti-CRMP4 antibody (ab36204)
Lane 1 : E.coli lysate transformed with cDNA of human CRMP1
Lane 2 : E.coli lysate transformed with cDNA of human CRMP2
Lane 3 : E.coli lysate transformed with cDNA of human CRMP3
Lane 4 : E.coli lysate transformed with cDNA of human CRMP4
Lane 5 : E.coli lysate transformed with cDNA of human CRMP5
Predicted band size: 65 kDa
Observed band size: 65 kDa
ab36204 has been referenced in 1 publication.
- Yoneda A et al. A collapsin response mediator protein 2 isoform controls myosin II-mediated cell migration and matrix assembly by trapping ROCK II. Mol Cell Biol 32:1788-804 (2012). PubMed: 22431514