Anti-CX3CL1 antibody (ab25091)
Key features and details
- Rabbit polyclonal to CX3CL1
- Suitable for: IP, WB
- Reacts with: Mouse
- Isotype: IgG
Overview
-
Product name
Anti-CX3CL1 antibody
See all CX3CL1 primary antibodies -
Description
Rabbit polyclonal to CX3CL1 -
Host species
Rabbit -
Specificity
ab25091 recognises CX3CL1 -
Tested applications
Suitable for: IP, WBmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Recombinant fragment: E. coli expressed chemotactic domain of mouse CX3CL1.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.1% Sodium azide
Constituent: 99.9% PBS -
Concentration information loading...
-
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab25091 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IP |
Use at an assay dependent concentration.
|
|
WB |
Use at an assay dependent concentration.
|
Notes |
---|
IP
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
Target
-
Function
The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. -
Tissue specificity
Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas. -
Sequence similarities
Belongs to the intercrine delta family. -
Post-translational
modificationsA soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form.
O-glycosylated with core 1 or possibly core 8 glycans. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
-
Database links
- Entrez Gene: 20312 Mouse
- SwissProt: O35188 Mouse
- Unigene: 103711 Mouse
-
Alternative names
- A 152E5.2 antibody
- AB030188 antibody
- ABCD 3 antibody
see all
Protocols
Datasheets and documents
-
SDS download
-
Datasheet download
References (2)
ab25091 has been referenced in 2 publications.
- Gong Q et al. Fractalkine aggravates LPS-induced macrophage activation and acute kidney injury via Wnt/ß-catenin signalling pathway. J Cell Mol Med 25:6963-6975 (2021). PubMed: 34101346
- Zhang Q et al. PSD-93 mediates the crosstalk between neuron and microglia and facilitates acute ischemic stroke injury by binding to CX3CL1. J Neurochem 157:2145-2157 (2021). PubMed: 33599284