Anti-CXCL5 antibody (ab18134)
Key features and details
- Rabbit polyclonal to CXCL5
- Suitable for: ELISA, WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-CXCL5 antibody
See all CXCL5 primary antibodies -
Description
Rabbit polyclonal to CXCL5 -
Host species
Rabbit -
Specificity
Specific for mouse lipopolysaccharide induced CXC chemokine (LIX). -
Tested applications
Suitable for: ELISA, WBmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Recombinant full length protein corresponding to Mouse CXCL5.
Database link: P50228 -
General notes
Mouse CXCL5 is the equivalent of human CXCL6 based on genetic and biological evidence as pointed out by Nomiyama et al. (PMID: 20434943).
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Constituent: PBS -
Concentration information loading...
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Purity
Protein A purified -
Purification notes
Purified by affinity chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab18134 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use a concentration of 0.5 - 2 µg/ml.
The detection limit is 0.2-0.4ng/well of recombinant mouse LIX |
|
WB |
Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 14 kDa.
|
Notes |
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ELISA
Use a concentration of 0.5 - 2 µg/ml. The detection limit is 0.2-0.4ng/well of recombinant mouse LIX |
WB
Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 14 kDa. |
Target
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Function
May participate in the recruitment of inflammatory cells by injured or infected tissue. GCP-2(1-78) and, more potent, GCP-2(9-78) attract neutrophils and are involved in neutrophil activation. -
Sequence similarities
Belongs to the intercrine alpha (chemokine CxC) family. -
Post-translational
modificationsGCP-2(1-78) and GCP-2(9-78) are produced by proteolytic cleavage after secretion from fibroblasts and epithelial cells. GCP-2(9-78) is the most prominent form. A number of additional N-terminal (processed between pos. 41 and 48) and C-terminal (processed between pos. 118 and 132) processed forms have been identified, probably also representing intermediate states. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 20311 Mouse
- SwissProt: P50228 Mouse
- Unigene: 4660 Mouse
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Alternative names
- C-X-C motif chemokine 5 antibody
- Cxcl5 antibody
- CXCL5_MOUSE antibody
see all
Datasheets and documents
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Datasheet download
References (1)
ab18134 has been referenced in 1 publication.
- Yu F et al. Deficiency of Kruppel-like factor KLF4 in mammary tumor cells inhibits tumor growth and pulmonary metastasis and is accompanied by compromised recruitment of myeloid-derived suppressor cells. Int J Cancer 133:2872-83 (2013). PubMed: 23737434