Anti-CXXC5 antibody (ab106533)
Key features and details
- Rabbit polyclonal to CXXC5
- Suitable for: ICC/IF, IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CXXC5 antibody
See all CXXC5 primary antibodies -
Description
Rabbit polyclonal to CXXC5 -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IF, IHC-P, WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide, 15 aa from near the amino terminus of human CXXC5 (NP_057547).
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Positive control
- Human brain tissue lysate.
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General notes
Predicted to not cross-react with other CXXC protein family members.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Primary antibody notes
Predicted to not cross-react with other CXXC protein family members. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab106533 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ICC/IF |
Use a concentration of 20 µg/ml.
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IHC-P |
Use a concentration of 2.5 µg/ml.
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 33 kDa. Isoform 2 predicted molecular weight 24 kDa
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Notes |
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ICC/IF
Use a concentration of 20 µg/ml. |
IHC-P
Use a concentration of 2.5 µg/ml. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 33 kDa. Isoform 2 predicted molecular weight 24 kDa |
Target
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Function
May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells. -
Sequence similarities
Contains 1 CXXC-type zinc finger. -
Cellular localization
Nucleus. Cytoplasm. Colocalizes with DVL1 in large bodies localized just outside the nuclear membrane. - Information by UniProt
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Database links
- Entrez Gene: 51523 Human
- Omim: 612752 Human
- SwissProt: Q7LFL8 Human
- Unigene: 189119 Human
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Form
There are 2 isoforms produced by alternative splicing. -
Alternative names
- CF5 antibody
- CXXC finger 5 protein antibody
- CXXC finger protein 5 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab106533 has been referenced in 2 publications.
- Yasar P et al. Estradiol-Estrogen Receptor a Mediates the Expression of the CXXC5 Gene through the Estrogen Response Element-Dependent Signaling Pathway. Sci Rep 6:37808 (2016). WB ; Human . PubMed: 27886276
- Kim HY et al. CXXC5 is a transcriptional activator of Flk-1 and mediates bone morphogenic protein-induced endothelial cell differentiation and vessel formation. FASEB J 28:615-26 (2014). WB ; Mouse . PubMed: 24136587