Anti-Choline Acetyltransferase antibody (ab18736)
Key features and details
- Sheep polyclonal to Choline Acetyltransferase
- Suitable for: ICC/IF
- Reacts with: Rat, Pig
- Isotype: IgG
Overview
-
Product name
Anti-Choline Acetyltransferase antibody
See all Choline Acetyltransferase primary antibodies -
Description
Sheep polyclonal to Choline Acetyltransferase -
Host species
Sheep -
Tested applications
Suitable for: ICC/IFmore details -
Species reactivity
Reacts with: Rat, Pig
Predicted to work with: Chicken -
Immunogen
Synthetic peptide:
GLFSSYRLPGHTQDTLVAQKSS
conjugated to KLH, corresponding to amino acids 167-188 of Pig Choline Acetyltransferase. -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Concentration information loading...
-
Purity
Ammonium Sulphate Precipitation -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Alternative Versions
-
Isotype control
-
Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab18736 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF |
Use at an assay dependent concentration.
|
Notes |
---|
ICC/IF
Use at an assay dependent concentration. |
Target
-
Function
Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. -
Involvement in disease
Myasthenic syndrome, congenital, 6, presynaptic -
Sequence similarities
Belongs to the carnitine/choline acetyltransferase family. - Information by UniProt
-
Database links
- Entrez Gene: 396896 Pig
- Entrez Gene: 290567 Rat
- SwissProt: P13222 Pig
- SwissProt: P32738 Rat
- Unigene: 45116 Rat
-
Alternative names
- Acetyl CoA choline O acetyltransferase antibody
- Acetyl CoA:choline O acetyltransferase antibody
- ChAT antibody
see all
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
SDS download
-
Datasheet download
References (37)
ab18736 has been referenced in 37 publications.
- Shi CJ et al. TGFβR-1/ALK5 inhibitor RepSox induces enteric glia-to-neuron transition and influences gastrointestinal mobility in adult mice. Acta Pharmacol Sin 44:92-104 (2023). PubMed: 35794374
- Miralles MP et al. Survival motor neuron protein and neurite degeneration are regulated by Gemin3 in spinal muscular atrophy motoneurons. Front Cell Neurosci 16:1054270 (2022). PubMed: 36619669
- Mullen PN et al. Kv3 Channels Contribute to the Excitability of Subpopulations of Spinal Cord Neurons in Lamina VII. eNeuro 9:N/A (2022). PubMed: 35058310
- Mu R et al. A cholinergic medial septum input to medial habenula mediates generalization formation and extinction of visual aversion. Cell Rep 39:110882 (2022). PubMed: 35649349
- Abot A et al. Identification of new enterosynes using prebiotics: roles of bioactive lipids and mu-opioid receptor signalling in humans and mice. Gut 70:1078-1087 (2021). PubMed: 33020209