Overview

  • Product name
    Clinofibrate
  • Description
    HMG-CoA reductase inhibitor. 3α-hydroxysteroid dehydrogenase inhibitor.
  • Biological description
    HMG-CoA reductase inhibitor (IC50 = 470 μM). Inhibits 3α-hydroxysteroid dehydrogenase (IC50 = 40 μM). Reduces plasma cholesterol levels and shows antihyperlipidemic effects in vivo. Orally active.
  • Purity
    > 99%

Properties

References

This product has been referenced in:
  • Imasaka S  et al. [Changes of lipids and lipoproteins in cholesterol free-high fructose diet-fed rats and the effects of clinofibrate]. Nihon Yakurigaku Zasshi 103:67-78 (1994). Read more (PubMed: 8112691) »
  • Yoshikuni Y  et al. Hypolipidemic effect of NS-1 and other related drugs in rhesus monkeys. Atherosclerosis 74:149-56 (1988). Read more (PubMed: 3214474) »
  • Shirai K  et al. Effect of clinofibrate on lipid metabolism of aorta in atherosclerotic rats. Artery 12:145-55 (1983). Read more (PubMed: 6680996) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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