Anti-Collagen XV alpha 1 antibody (ab58717)
Key features and details
- Rabbit polyclonal to Collagen XV alpha 1
- Suitable for: WB, ELISA
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Collagen XV alpha 1 antibody -
Description
Rabbit polyclonal to Collagen XV alpha 1 -
Host species
Rabbit -
Tested applications
Suitable for: WB, ELISAmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Synthetic peptide corresponding to C terminal residues of human Collagen XV alpha 1.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Purified by antigen specific affinity chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab58717 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use at an assay dependent concentration.
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ELISA |
Use at an assay dependent concentration.
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Notes |
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WB
Use at an assay dependent concentration. |
ELISA
Use at an assay dependent concentration. |
Target
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Function
Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle.
Restin potently inhibits angiogenesis. -
Tissue specificity
Expressed predominantly in internal organs such as adrenal gland, pancreas and kidney. -
Sequence similarities
Belongs to the multiplexin collagen family.
Contains 4 collagen-like domains.
Contains 1 laminin G-like domain. -
Post-translational
modificationsProlines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
O-glycosylated; with core 1 or possibly core 8 glycans. An N-terminal peptide contains chondroitin sulfate. -
Cellular localization
Secreted, extracellular space, extracellular matrix. - Information by UniProt
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Database links
- Entrez Gene: 1306 Human
- Entrez Gene: 12819 Mouse
- Omim: 120325 Human
- SwissProt: P39059 Human
- SwissProt: O35206 Mouse
- Unigene: 409034 Human
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Alternative names
- Alpha 1 type XV collagen antibody
- COFA1_HUMAN antibody
- COL15A1 antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab58717 has been referenced in 1 publication.
- Fan H et al. Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis. Cell Rep 33:108473 (2020). PubMed: 33296650