Anti-Cyclin K antibody (ab251652)
Key features and details
- Rabbit polyclonal to Cyclin K
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-Cyclin K antibody
See all Cyclin K primary antibodies -
Description
Rabbit polyclonal to Cyclin K -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IFmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Recombinant fragment corresponding to Human Cyclin K aa 1-200.
Database link: O75909 -
Positive control
- ICC/IF: MCF7 cells.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Recombinant Protein
-
Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab251652 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
Fixation/Permeabilization: PFA/Triton X-100. |
Notes |
---|
ICC/IF
Use a concentration of 0.25 - 2 µg/ml. Fixation/Permeabilization: PFA/Triton X-100. |
Target
-
Function
May play a role in transcriptional regulation. In vitro, is associated with a kinase activity toward both RNA polymerase II C-terminal domain and CDK2 (CAK). -
Tissue specificity
Ubiquitously expressed. Highest levels in testis. -
Sequence similarities
Belongs to the cyclin family. Cyclin C subfamily. - Information by UniProt
-
Database links
- Entrez Gene: 8812 Human
- Entrez Gene: 12454 Mouse
- Omim: 603544 Human
- SwissProt: O75909 Human
- SwissProt: O88874 Mouse
- Unigene: 510409 Human
- Unigene: 474441 Mouse
-
Alternative names
- CCNK antibody
- CCNK_HUMAN antibody
- CPR 4 antibody
see all
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
SDS download
-
Datasheet download
References (1)
ab251652 has been referenced in 1 publication.
- Slabicki M et al. The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K. Nature 585:293-297 (2020). PubMed: 32494016