Anti-DEFA6 antibody (ab72577)
Key features and details
- Mouse polyclonal to DEFA6
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-DEFA6 antibody
See all DEFA6 primary antibodies -
Description
Mouse polyclonal to DEFA6 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein within Human DEFA6. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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Positive control
- DEFA6 transfected 293T cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.40
Constituent: PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab72577 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Predicted molecular weight: 11 kDa.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 11 kDa. |
Target
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Function
Has very low antimicrobial activity against Gram-negative and Gram-positive bacteria. May protect cells against infection with HIV-1. -
Tissue specificity
Paneth cells of the small intestine. -
Sequence similarities
Belongs to the alpha-defensin family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 1671 Human
- Omim: 600471 Human
- SwissProt: Q01524 Human
- Unigene: 711 Human
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Alternative names
- alpha 6 antibody
- DEF6 antibody
- DEF6_HUMAN antibody
see all
Images
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All lanes : Anti-DEFA6 antibody (ab72577) at 1/500 dilution
Lane 1 : DEFA6 transfected 293T cell lysate
Lane 2 : Non transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution
Developed using the ECL technique.
Predicted band size: 11 kDa
Observed band size: 11 kDa
Datasheets and documents
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Datasheet download
References (1)
ab72577 has been referenced in 1 publication.
- Stronati L et al. Altered expression of innate immunity genes in different intestinal sites of children with ulcerative colitis. Dig Liver Dis 42:848-53 (2010). WB ; Human . PubMed: 20452301