Anti-MKP-1 (phospho S359) antibody (ab63548)
Key features and details
- Rabbit polyclonal to MKP-1 (phospho S359)
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MKP-1 (phospho S359) antibody
See all MKP-1 primary antibodies -
Description
Rabbit polyclonal to MKP-1 (phospho S359) -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Synthetic peptide corresponding to Human MKP-1 aa 300-400 (phospho S359).
Database link: P28562 -
Positive control
- Human lung carcinoma tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Without Mg2+ and Ca2+ -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab63548 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
1/50 - 1/100.
|
Notes |
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IHC-P
1/50 - 1/100. |
Target
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Function
Dual specificity phosphatase that dephosphorylates MAP kinase ERK2 on both 'Thr-183' and 'Tyr-185'. -
Tissue specificity
Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney. -
Sequence similarities
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 rhodanese domain.
Contains 1 tyrosine-protein phosphatase domain. - Information by UniProt
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Database links
- Entrez Gene: 1843 Human
- Entrez Gene: 19252 Mouse
- Omim: 600714 Human
- SwissProt: P28562 Human
- SwissProt: P28563 Mouse
- Unigene: 171695 Human
- Unigene: 239041 Mouse
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Alternative names
- CL 100 antibody
- CL100 antibody
- Dual Specificity Phosphatase 1 antibody
see all
Images
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ab36548 at 1/50-1/100 dilution staining human lung carcinoma tissue, without (left) and with (right) immunizing peptide; paraffin embedded.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab63548 has not yet been referenced specifically in any publications.