Anti-Dab1 (phospho Y232) antibody (ab78200)
Key features and details
- Rabbit polyclonal to Dab1 (phospho Y232)
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Dab1 (phospho Y232) antibody
See all Dab1 primary antibodies -
Description
Rabbit polyclonal to Dab1 (phospho Y232) -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide corresponding to Human Dab1 (phospho Y232).
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Positive control
- Extracts from LOVO cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab78200 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa).
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Notes |
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WB
1/500 - 1/1000. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa). |
Target
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Function
Adapter molecule functioning in neural development. May regulate SIAH1 activity. -
Sequence similarities
Contains 1 PID domain. -
Domain
The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins. -
Post-translational
modificationsPhosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling. - Information by UniProt
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Database links
- Entrez Gene: 1600 Human
- Entrez Gene: 13131 Mouse
- Entrez Gene: 266729 Rat
- Omim: 603448 Human
- SwissProt: O75553 Human
- SwissProt: P97318 Mouse
- SwissProt: Q8CJH2 Rat
- Unigene: 477370 Human
see all -
Alternative names
- Dab 1 antibody
- Dab reelin signal transducer 1 antibody
- Dab, reelin signal transducer, homolog 1 (Drosophila) antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab78200 has been referenced in 2 publications.
- Racetin A et al. Expression and localization of DAB1 and Reelin during normal human kidney development. Croat Med J 60:521-531 (2019). PubMed: 31894918
- Rogers JT et al. Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density. Learn Mem 18:558-64 (2011). PubMed: 21852430