Product nameAnti-Dact2 antibody
See all Dact2 primary antibodies
DescriptionRabbit polyclonal to Dact2
Tested applicationsSuitable for: WB, ELISA, ICC/IFmore details
Species reactivityReacts with: Mouse, Rat, Human
A 12 amino acid synthetic peptide from near the amino terminus of human Dact2 (NP_999627).
- SK N SH cell lysate
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab79042 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 83 kDa.|
|ELISA||Use at an assay dependent dilution.|
|ICC/IF||Use a concentration of 20 µg/ml.|
FunctionNegatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors.
Sequence similaritiesBelongs to the dapper family.
DomainThe C-terminal PDZ-binding motif may mediate interaction with the PDZ domains of DSH (Dishevelled) family proteins.
- Information by UniProt
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This product has been referenced in:
- Guo YL et al. Aberrant methylation of DACT1 and DACT2 are associated with tumor progression and poor prognosis in esophageal squamous cell carcinoma. J Biomed Sci 24:6 (2017). IHC-P ; Human . Read more (PubMed: 28077137) »
- Hou J et al. DACT2 is a candidate tumor suppressor and prognostic marker in esophageal squamous cell carcinoma. Cancer Prev Res (Phila) 6:791-800 (2013). Read more (PubMed: 23803417) »