Anti-ENPP6 antibody (ab127897)
Key features and details
- Rabbit polyclonal to ENPP6
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ENPP6 antibody
See all ENPP6 primary antibodies -
Description
Rabbit polyclonal to ENPP6 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 15-207 of Human ENPP6 (Q6UWR7).
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Positive control
- MCF7 whole cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab127897 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 50 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 50 kDa. |
Target
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Relevance
ENPP6 is a choline-specific glycerophosphodiester phosphodiesterase, which hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5 prime-monophosphate. It hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. ENPP6 has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. ENPP6 also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently. ENPP6 is predominantly expressed in kidney and brain. -
Cellular localization
Cell membrane; Single-pass type I membrane protein. Secreted. Note: A minor secreted form also exists. -
Database links
- Entrez Gene: 537431 Cow
- Entrez Gene: 133121 Human
- Entrez Gene: 320981 Mouse
- Entrez Gene: 306460 Rat
- SwissProt: Q58D68 Cow
- SwissProt: Q6UWR7 Human
- SwissProt: Q8BGN3 Mouse
- SwissProt: B0BND0 Rat
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Alternative names
- B830047L21Rik antibody
- E-NPP 6 antibody
- Ectonucleotide pyrophosphatase/phosphodiesterase 6 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab127897 has been referenced in 1 publication.
- Aranmolate A et al. Myelination is delayed during postnatal brain development in the mdx mouse model of Duchenne muscular dystrophy. BMC Neurosci 18:63 (2017). PubMed: 28806929