Anti-FAM172A antibody (ab121364)
Key features and details
- Rabbit polyclonal to FAM172A
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-FAM172A antibody -
Description
Rabbit polyclonal to FAM172A -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IFmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Recombinant fragment within Human FAM172A aa 1-150. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: Q8WUF8 -
Positive control
- ICC/IF: U-251 MG cells;
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab121364 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
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Notes |
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ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
Target
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Sequence similarities
Belongs to the UPF0528 family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 83989 Human
- Entrez Gene: 68675 Mouse
- Entrez Gene: 294606 Rat
- SwissProt: Q8WUF8 Human
- SwissProt: Q3TNH5 Mouse
- Unigene: 600086 Human
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Alternative names
- C5orf21 antibody
- F172A_HUMAN antibody
- fam172a antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (7)
ab121364 has been referenced in 7 publications.
- Bélanger C et al. CHARGE syndrome-associated proteins FAM172A and CHD7 influence male sex determination and differentiation through transcriptional and alternative splicing mechanisms. FASEB J 36:e22176 (2022). PubMed: 35129866
- Chen Y et al. FAM172A inhibits EMT in pancreatic cancer via ERK-MAPK signaling. Biol Open 9:N/A (2020). PubMed: 31988090
- Xiao F et al. FAM172A Deletion May Enhance Hepatic Steatosis by Promoting ER Stress. Dig Dis Sci N/A:N/A (2020). PubMed: 32945983
- Xu AM et al. FAM172A affects cell proliferation and apoptosis not by targeting β-tubulin in HepG2 cells. Transl Cancer Res 9:5637-5644 (2020). PubMed: 35117927
- Liu W et al. Expression of family with sequence similarity 172 member A and nucleotide-binding protein 1 is associated with the poor prognosis of colorectal carcinoma. Oncol Lett 14:3587-3593 (2017). PubMed: 28927116
- Liu W et al. miR-27a promotes proliferation, migration, and invasion of colorectal cancer by targeting FAM172A and acts as a diagnostic and prognostic biomarker. Oncol Rep 37:3554-3564 (2017). PubMed: 28440497
- Li MF et al. FAM172A protein promotes the proliferation of human papillary thyroid carcinoma cells via the p38 mitogen-activated protein kinase pathway. Mol Med Rep 13:353-8 (2016). PubMed: 26573560