Anti-Flt3 / CD135 antibody [RM0021-12B6] (ab73019)
Key features and details
- Rat monoclonal [RM0021-12B6] to Flt3 / CD135
- Suitable for: IHC-P
- Reacts with: Mouse
- Isotype: IgG2
Overview
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Product name
Anti-Flt3 / CD135 antibody [RM0021-12B6]
See all Flt3 / CD135 primary antibodies -
Description
Rat monoclonal [RM0021-12B6] to Flt3 / CD135 -
Host species
Rat -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
produced from a hybridoma (mouse myeloma) fused with spleen cells from a rat immunized with purified recombinant mouse Flt3/ CD135 extracellular domain.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Lyophilized:Reconstitute the antibody with 500 µl sterile PBS. -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Constituent: PBS -
Concentration information loading...
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Purity
Protein G purified -
Purification notes
Purified from tissue culture supernatant. Filter sterilised. -
Clonality
Monoclonal -
Clone number
RM0021-12B6 -
Isotype
IgG2 -
Research areas
Associated products
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Compatible Secondaries
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab73019 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50 - 1/100.
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Notes |
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IHC-P
1/50 - 1/100. |
Target
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Function
Receptor for the FL cytokine. Has a tyrosine-protein kinase activity. -
Tissue specificity
Bone marrow cells. -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 protein kinase domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 14255 Mouse
- SwissProt: Q00342 Mouse
- Unigene: 194 Mouse
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Alternative names
- CD 135 antibody
- CD135 antibody
- CD135 antigen antibody
see all
Images
Datasheets and documents
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Datasheet download
References (2)
ab73019 has been referenced in 2 publications.
- Crapser JD et al. Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease. Brain 143:266-288 (2020). PubMed: 31848580
- Svensson MN et al. Murine germinal center B cells require functional Fms-like tyrosine kinase 3 signaling for IgG1 class-switch recombination. Proc Natl Acad Sci U S A 112:E6644-53 (2015). IHC ; Mouse . PubMed: 26627255