Fumitremorgin C (Tryptoquivaline), Chemosensitizing agent (ab144258)
Key features and details
- Chemosensitizing agent. Potent and selective BCRP inhibitor. Selective AKT inhibitor.
- CAS Number: 118974-02-0
- Purity: > 98%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Aspergillus fumigatus
Overview
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Product name
Fumitremorgin C (Tryptoquivaline), Chemosensitizing agent -
Description
Chemosensitizing agent. Potent and selective BCRP inhibitor. Selective AKT inhibitor. -
Purity
> 98% -
CAS Number
118974-02-0 -
Chemical structure
Properties
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Chemical name
(5aS,12S,14aS)-1,2,5a,6,11,12,14a-Octahydro-9-methoxy-12-(2-methylprop-1-en-1-yl)-5H,14H-pyrrolo[1'',4'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione -
Molecular weight
379.45 -
Molecular formula
C22H25N3O3 -
PubChem identifier
403923 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=C[C@H]1C2=C(C[C@@H]3N1C(=O)[C@@H]4CCCN4C3=O)C5=C(N2)C=C(C=C5)OC)C -
Source
Aspergillus fumigatus
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Research areas
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab144258 has been referenced in 1 publication.
- Šimecková Š et al. High Skp2 expression is associated with a mesenchymal phenotype and increased tumorigenic potential of prostate cancer cells. Sci Rep 9:5695 (2019). PubMed: 30952903