Fura-2 K+ salt, fluorescent Ca2+ binding dye (ab142777)
Key features and details
- Fluorescent Ca2+ binding dye. Cell membrane impermeable.
- CAS Number: 113694-64-7
- Purity: > 95%
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Fura-2 K+ salt, fluorescent Ca2+ binding dye -
Description
Fluorescent Ca2+ binding dye. Cell membrane impermeable. -
Purity
> 95% -
CAS Number
113694-64-7 -
Chemical structure
Properties
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Excitation
340nm -
Emission
505nm -
Chemical name
2-[6-[Bis(carboxylatomethyl)amino]-5-[2-[2-[bis(carboxylatomethyl)amino]-5-methylphenoxy]ethoxy]-1-benzofuran-2-yl]-1,3-oxazole-5-carboxylate pentapotassium salt -
Molecular weight
832.00 -
Molecular formula
C29H22K5N3O14 -
PubChem identifier
6098363 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC(=C(C=C1)N(CC(=O)[O-])CC(=O)[O-])OCCOC2=C(C=C3C(=C2)C=C(O3)C4=NC=C(O4)C(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[K+].[K+].[K+].[K+].[K+] -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (2)
ab142777 has been referenced in 2 publications.
- La Barbera L et al. Upregulation of Ca2+-binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer's disease in Tg2576 mice. Mol Neurodegener 17:76 (2022). PubMed: 36434727
- Krashia P et al. Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease. Nat Commun 10:3945 (2019). PubMed: 31477726