Overview

  • Product name

    Anti-GABA A Receptor alpha 6 antibody
    See all GABA A Receptor alpha 6 primary antibodies
  • Description

    Rabbit polyclonal to GABA A Receptor alpha 6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ELISA, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to an internal region of Human GABA A Receptor alpha 6.

  • Positive control

    • HeLa or Jurkat cell extracts

Properties

Applications

Our Abpromise guarantee covers the use of ab92747 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notes
    ELISA: 1/40000.
    WB: 1/500 - 1/1000. Predicted molecular weight: 51 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
    • Sequence similarities

      Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA6 sub-subfamily.
    • Cellular localization

      Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • GABA A antibody
      • GABA A Receptor alpha 6 polypeptide antibody
      • GABA A receptor alpha 6 antibody
      • GABA A receptor subunit alpha 6 antibody
      • GABA subunit A receptor alpha 6 antibody
      • GABA(A) receptor subunit alpha-6 antibody
      • GABRA 6 antibody
      • GABRA6 antibody
      • Gamma aminobutyric acid A receptor alpha 6 antibody
      • Gamma aminobutyric acid GABA A receptor alpha 6 antibody
      • Gamma aminobutyric acid receptor subunit alpha 6 antibody
      • Gamma-aminobutyric acid receptor subunit alpha-6 antibody
      • GBRA6_HUMAN antibody
      • MGC116903 antibody
      • MGC116904 antibody
      see all

    Images

    • All lanes : Anti-GABA A Receptor alpha 6 antibody (ab92747) at 1/500 dilution

      Lane 1 : Jurkat cell extracts
      Lane 2 : HeLa cell extracts
      Lane 3 : HeLa cell extracts with immunizing peptide at 10 µg

      Lysates/proteins at 20 µg per lane.

      Predicted band size: 51 kDa

    References

    This product has been referenced in:

    • Fan PC  et al. The a6 subunit-containing GABAA receptor: A novel drug target for inhibition of trigeminal activation. Neuropharmacology 140:1-13 (2018). Read more (PubMed: 30016665) »
    See 1 Publication for this product

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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