Anti-GPCR GPR31 antibody (ab75579)
Key features and details
- Rabbit polyclonal to GPCR GPR31
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-GPCR GPR31 antibody
See all GPCR GPR31 primary antibodies -
Description
Rabbit polyclonal to GPCR GPR31 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- Extracts from COLO cells
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 0.87% Sodium chloride, 50% Glycerol (glycerin, glycerine), PBS
Without Mg2+ and Ca2+ -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab75579 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab75579 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Predicted molecular weight: 35 kDa.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 35 kDa. |
Target
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Relevance
GPCR GPR31 is a member of the G protein coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. GPCR GPR31 is located on human chromosome 6q27. -
Cellular localization
Cell membrane; Multi pass membrane protein -
Database links
- Entrez Gene: 2853 Human
- Omim: 602043 Human
- SwissProt: O00270 Human
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Alternative names
- 12-(S)-HETE acid receptor antibody
- 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (HETE) receptor antibody
- 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab75579 has been referenced in 5 publications.
- Sun Z et al. LINE-1 promotes tumorigenicity and exacerbates tumor progression via stimulating metabolism reprogramming in non-small cell lung cancer. Mol Cancer 21:147 (2022). PubMed: 35842613
- Förch A et al. Expression of Proton-Sensitive GPR31, GPR151, TASK1 and TASK3 in Common Skin Tumors. Cells 11:N/A (2021). PubMed: 35011589
- Otto M et al. 12(S)-HETE mediates diabetes-induced endothelial dysfunction by activating intracellular endothelial cell TRPV1. J Clin Invest 130:4999-5010 (2020). PubMed: 32584793
- Yang F et al. Ischemia reperfusion injury promotes recurrence of hepatocellular carcinoma in fatty liver via ALOX12-12HETE-GPR31 signaling axis. J Exp Clin Cancer Res 38:489 (2019). PubMed: 31831037
- Siangjong L et al. Endothelial 12(S)-HETE vasorelaxation is mediated by thromboxane receptor inhibition in mouse mesenteric arteries. Am J Physiol Heart Circ Physiol 304:H382-92 (2013). WB ; Mouse . PubMed: 23203967