Anti-GSDMD antibody (ab155233)
Key features and details
- Rabbit polyclonal to GSDMD
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-GSDMD antibody
See all GSDMD primary antibodies -
Description
Rabbit polyclonal to GSDMD -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human GSDMD aa 1-200.
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Positive control
- A431 whole cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 78% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab155233 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 53 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 53 kDa. |
Target
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Sequence similarities
Belongs to the gasdermin family. - Information by UniProt
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Database links
- Entrez Gene: 79792 Human
- Omim: 617042 Human
- SwissProt: P57764 Human
- Unigene: 118983 Human
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Alternative names
- 1810036L03Rik antibody
- DF 5L antibody
- DF5L antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (6)
ab155233 has been referenced in 6 publications.
- Xue Y et al. Citrulline protects against LPS‑induced acute lung injury by inhibiting ROS/NLRP3‑dependent pyroptosis and apoptosis via the Nrf2 signaling pathway. Exp Ther Med 24:632 (2022). PubMed: 36160882
- Dhar R et al. Time‑dependent changes in NLRP3 and Nrf2 levels in lipopolysaccharide‑induced acute lung injury. Int J Mol Med 50:N/A (2022). PubMed: 36321790
- Yokoyama S et al. Secretoglobin 3A2 eliminates human cancer cells through pyroptosis. Cell Death Discov 7:12 (2021). PubMed: 33452234
- Ku JWK et al. Skin models for cutaneous melioidosis reveal Burkholderia infection dynamics at wound's edge with inflammasome activation, keratinocyte extrusion and epidermal detachment. Emerg Microbes Infect 10:2326-2339 (2021). PubMed: 34821529
- Dasari TK et al. The nonreceptor tyrosine kinase SYK drives caspase-8/NLRP3 inflammasome-mediated autoinflammatory osteomyelitis. J Biol Chem 295:3394-3400 (2020). PubMed: 31719149
- Xi G et al. GSDMD is required for effector CD8+ T cell responses to lung cancer cells. Int Immunopharmacol 74:105713 (2019). PubMed: 31276977