GSK429286A, ROCK1 and ROCK2 inhibitor (ab146581)
Key features and details
- Selective ROCK1 and ROCK2 inhibitor
- CAS Number: 864082-47-3
- Purity: > 98%
- Soluble in DMSO to 100 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GSK429286A, ROCK1 and ROCK2 inhibitor -
Description
Selective ROCK1 and ROCK2 inhibitor -
Purity
> 98% -
General notes
This product is manufactured by BioVision, an Abcam company and was previously called 2637 GSK429286A. 2637-5 is the same size as the 5 mg size of ab146581.
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CAS Number
864082-47-3 -
Chemical structure
Properties
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Chemical name
4-[4-(Trifluoromethyl)phenyl]-N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxamide -
Molecular weight
432.37 -
Molecular formula
C21H16F4N4O2 -
PubChem identifier
11373846 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=C(C(CC(=O)N1)C2=CC=C(C=C2)C(F)(F)F)C(=O)NC3=C(C=C4C(=C3)C=NN4)F -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab146581 has not yet been referenced specifically in any publications.