Recombinant Anti-HIV1 p24 antibody [P131] (ab32352)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [P131] to HIV1 p24
- Suitable for: WB
- Reacts with: Human immunodeficiency virus
Related conjugates and formulations
Overview
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Product name
Anti-HIV1 p24 antibody [P131]
See all HIV1 p24 primary antibodies -
Description
Rabbit monoclonal [P131] to HIV1 p24 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human immunodeficiency virus -
Immunogen
Recombinant full length protein corresponding to HIV1 p24.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
P131 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab32352 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/10000. Detects a band of approximately 24 kDa (predicted molecular weight: 24 kDa).
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Notes |
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WB
1/10000. Detects a band of approximately 24 kDa (predicted molecular weight: 24 kDa). |
Target
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Relevance
HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. -
Cellular localization
Membrane -
Database links
- SwissProt: P04585 Human immunodeficiency virus
- SwissProt: P12497 Human immunodeficiency virus
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Alternative names
- CA antibody
- Capsid protein p24 antibody
- HIV-1 Gag p24 antibody
see all
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab32352 has been referenced in 3 publications.
- Wei G et al. Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection. Nat Commun 13:5879 (2022). PubMed: 36202818
- Kim K et al. Cyclophilin A protects HIV-1 from restriction by human TRIM5a. Nat Microbiol 4:2044-2051 (2019). PubMed: 31636416
- Xi W et al. Incorporation of CD40 ligand enhances the immunogenicity of tumor-associated calcium signal transducer 2 virus-like particles against lung cancer. Int J Mol Med 41:3671-3679 (2018). PubMed: 29568866