Overview

  • Product name

  • Description

    Rabbit polyclonal to HSD17B2
  • Host species

    Rabbit
  • Specificity

    ab196784 detects endogenous level of total HSD17B2 protein.
  • Tested applications

    Suitable for: ICC/IF, IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment corresponding to Human HSD17B2 (C terminal).
    Database link: P37059

  • Positive control

    • SW480 cell extracts. Mouse liver, kidney, craniofacial and intestine extracts. U2OS cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.4
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 50% Glycerol, 0.87% Sodium chloride

    PBS without Mg2+ and Ca2+.
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab196784 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/50 - 1/200.
IHC-P 1/50 - 1/200.
WB 1/500 - 1/2000. Predicted molecular weight: 43 kDa.

Target

  • Function

    Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.
  • Sequence similarities

    Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 17 beta HSD 2 antibody
    • 17-beta-HSD 2 antibody
    • 17-beta-hydroxysteroid dehydrogenase type 2 antibody
    • 20 alpha HSD antibody
    • 20 alpha hydroxysteroid dehydrogenase antibody
    • 20 alpha-hydroxysteroid dehydrogenase antibody
    • 20-alpha-HSD antibody
    • DHB2_HUMAN antibody
    • E2DH antibody
    • EDH17B2 antibody
    • Estradiol 17-beta-dehydrogenase 2 antibody
    • HSD17 antibody
    • Hsd17b2 antibody
    • Hydroxysteroid (17 beta) dehydrogenase 2 antibody
    • Microsomal 17 beta hydroxysteroid dehydrogenase antibody
    • Microsomal 17-beta-hydroxysteroid dehydrogenase antibody
    • SDR9C2 antibody
    • Short chain dehydrogenase/reductase family 9C, member 2 antibody
    • Testosterone 17 beta dehydrogenase antibody
    • Testosterone 17-beta-dehydrogenase antibody
    see all

Images

  • All lanes : Anti-HSD17B2 antibody (ab196784) at 1/500 dilution

    Lane 1 : SW480 cell extracts
    Lane 2 : Mouse liver cell extracts
    Lane 3 : Mouse kidney cell extracts
    Lane 4 : Mouse craniofacial cell extracts
    Lane 5 : Mouse intestines cell extracts

    Predicted band size: 43 kDa

  • Immunofluorescent analysis of U20S cells, labeling HSD17B2 (green) with ab196784 at 1/50 dilution. Blue: DAPI for nuclear staining. 

References

ab196784 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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