Overview

  • Product name

  • Description

    Mouse polyclonal to HSD17B2
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length HSD17B2 protein (Human)

  • Positive control

    • HSD17B2 transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab67179 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 37 kDa (predicted molecular weight: 43 kDa).

Target

  • Function

    Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.
  • Sequence similarities

    Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 17 beta HSD 2 antibody
    • 17-beta-HSD 2 antibody
    • 17-beta-hydroxysteroid dehydrogenase type 2 antibody
    • 20 alpha HSD antibody
    • 20 alpha hydroxysteroid dehydrogenase antibody
    • 20 alpha-hydroxysteroid dehydrogenase antibody
    • 20-alpha-HSD antibody
    • DHB2_HUMAN antibody
    • E2DH antibody
    • EDH17B2 antibody
    • Estradiol 17-beta-dehydrogenase 2 antibody
    • HSD17 antibody
    • Hsd17b2 antibody
    • Hydroxysteroid (17 beta) dehydrogenase 2 antibody
    • Microsomal 17 beta hydroxysteroid dehydrogenase antibody
    • Microsomal 17-beta-hydroxysteroid dehydrogenase antibody
    • SDR9C2 antibody
    • Short chain dehydrogenase/reductase family 9C, member 2 antibody
    • Testosterone 17 beta dehydrogenase antibody
    • Testosterone 17-beta-dehydrogenase antibody
    see all

Images

  • All lanes : Anti-HSD17B2 antibody (ab67179) at 1/500 dilution

    Lane 1 : HSD17B2 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg/ml per lane.

    Secondary
    All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size: 43 kDa
    Observed band size: 37 kDa
    why is the actual band size different from the predicted?

References

This product has been referenced in:

  • Zhang CY  et al. The contribution of 17beta-hydroxysteroid dehydrogenase type 1 to the estradiol-estrone ratio in estrogen-sensitive breast cancer cells. PLoS One 7:e29835 (2012). WB ; Human . Read more (PubMed: 22253796) »
See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab67179.
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