Anti-IL22 RA2/IL-22BP antibody (ab18566)
Key features and details
- Goat polyclonal to IL22 RA2/IL-22BP
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-IL22 RA2/IL-22BP antibody
See all IL22 RA2/IL-22BP primary antibodies -
Description
Goat polyclonal to IL22 RA2/IL-22BP -
Host species
Goat -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide corresponding to Human IL22 RA2/IL-22BP aa 33-60 (N terminal).
Sequence:RVQFQSRNFHNILQWQPGRALTGNSSVYC
Database link: Q969J5 -
Positive control
- Human spleen or tonsil.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.40
Preservative: 0.1% Sodium azide
Constituents: 0.21% Potassium phosphate, 0.812% Sodium chloride -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab18566 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
1/300.
|
Notes |
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IHC-P
1/300. |
Target
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Function
Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.
Isoform 1 may play a role in establishing and maintaining successful pregnancy. -
Tissue specificity
Expressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach. -
Sequence similarities
Belongs to the type II cytokine receptor family.
Contains 3 fibronectin type-III domains. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 116379 Human
- Entrez Gene: 237310 Mouse
- Entrez Gene: 444986 Rat
- Omim: 606648 Human
- SwissProt: Q969J5 Human
- SwissProt: Q80XF5 Mouse
- SwissProt: Q7TNI4 Rat
- Unigene: 126891 Human
see all -
Alternative names
- IL 22BP antibody
- IL 22RA2 antibody
- IL22RA2 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab18566 has not yet been referenced specifically in any publications.