Anti-KDEL Receptor antibody [2E7] (ab96720)
Key features and details
- Mouse monoclonal [2E7] to KDEL Receptor
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG2b
Overview
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Product name
Anti-KDEL Receptor antibody [2E7]
See all KDEL Receptor primary antibodies -
Description
Mouse monoclonal [2E7] to KDEL Receptor -
Host species
Mouse -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Saccharomyces cerevisiae KDEL Receptor (C terminal).
Database link: P18414 -
Positive control
- IHC-P: Human kidney tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
2E7 -
Isotype
IgG2b -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96720 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
Use at an assay dependent concentration.
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Notes |
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IHC-P
Use at an assay dependent concentration. |
Target
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Function
Required for the retention of luminal endoplasmic reticulum resident proteins via vesicular recycling. This receptor recognizes the C-terminal K-D-E-L motif. COPI-coated transport intermediates, either in the form of round vesicles or as tubular processes, mediate retrograde traffic of the KDEL receptor-ligand complexes. Also required for normal vesicular traffic through the Golgi. -
Sequence similarities
Belongs to the ERD2 family. -
Post-translational
modificationsPhosphorylation by PKA at Ser-209 is required for endoplasmic reticulum retention function. -
Cellular localization
Cytoplasmic vesicle, COPI-coated vesicle membrane. Endoplasmic reticulum membrane. Endoplasmic reticulum-Golgi intermediate compartment membrane. - Information by UniProt
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Database links
- Entrez Gene: 10945 Human
- Omim: 131235 Human
- SwissProt: P24390 Human
- Unigene: 515515 Human
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Alternative names
- ER lumen protein retaining receptor 1 antibody
- ER lumen protein-retaining receptor 1 antibody
- ERD 2 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab96720 has not yet been referenced specifically in any publications.