Overview

  • Product name

    Anti-KRTHB3 antibody [EPR12333-112] - BSA and Azide free
    See all KRTHB3 primary antibodies
  • Description

    Rabbit monoclonal [EPR12333-112] to KRTHB3 - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human KRTHB3. The exact sequence is proprietary.
    Database link: P78385

  • General notes

    ab249868 is the carrier-free version of ab175217 This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    Ab249868 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab249868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 54 kDa.
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Tissue specificity

      Synthesis begins in the cortex 10-15 cell layers above the apex of the dermal papilla and ends abruptly in the middle of the cortex.
    • Involvement in disease

      Defects in KRT83 are a cause of monilethrix (MLTRX) [MIM:158000]. Monilethrix is an autosomal dominant hair disorder characterized clinically by alopecia and follicular papules. Affected hairs have uniform elliptical nodes of normal thickness and intermittent constrictions, internodes at which the hair easily breaks. Usually only the scalp is involved, but in severe forms, the secondary sexual hair, eyebrows, eyelashes, and nails may also be affected.
    • Sequence similarities

      Belongs to the intermediate filament family.
    • Information by UniProt
    • Database links

    • Alternative names

      • Hair keratin K2.10 antibody
      • Hard keratin, type II, 3 antibody
      • HB 3 antibody
      • HB3 antibody
      • hHb3 antibody
      • K2.10 antibody
      • K83 antibody
      • Keratin 83 antibody
      • Keratin antibody
      • Keratin, hair, basic, 3 antibody
      • Keratin-83 antibody
      • Krt83 antibody
      • KRT83_HUMAN antibody
      • KRTHB3 antibody
      • type II cuticular Hb3 antibody
      • Type II hair keratin Hb3 antibody
      • Type-II keratin Kb23 antibody
      see all

    References

    ab249868 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab249868.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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