Overview

  • Product name

    Anti-KRTHB3 antibody [EPR12333-112]
    See all KRTHB3 primary antibodies
  • Description

    Rabbit monoclonal [EPR12333-112] to KRTHB3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human KRTHB3. The exact sequence is proprietary.
    Database link: P78385

  • Positive control

    • Human skin lysate.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity

    Tissue culture supernatant
  • Clonality

    Monoclonal
  • Clone number

    EPR12333-112
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab175217 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000 - 1/50000. Predicted molecular weight: 54 kDa.
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Tissue specificity

      Synthesis begins in the cortex 10-15 cell layers above the apex of the dermal papilla and ends abruptly in the middle of the cortex.
    • Involvement in disease

      Defects in KRT83 are a cause of monilethrix (MLTRX) [MIM:158000]. Monilethrix is an autosomal dominant hair disorder characterized clinically by alopecia and follicular papules. Affected hairs have uniform elliptical nodes of normal thickness and intermittent constrictions, internodes at which the hair easily breaks. Usually only the scalp is involved, but in severe forms, the secondary sexual hair, eyebrows, eyelashes, and nails may also be affected.
    • Sequence similarities

      Belongs to the intermediate filament family.
    • Information by UniProt
    • Database links

    • Alternative names

      • Hair keratin K2.10 antibody
      • Hard keratin, type II, 3 antibody
      • HB 3 antibody
      • HB3 antibody
      • hHb3 antibody
      • K2.10 antibody
      • K83 antibody
      • Keratin 83 antibody
      • Keratin antibody
      • Keratin, hair, basic, 3 antibody
      • Keratin-83 antibody
      • Krt83 antibody
      • KRT83_HUMAN antibody
      • KRTHB3 antibody
      • type II cuticular Hb3 antibody
      • Type II hair keratin Hb3 antibody
      • Type-II keratin Kb23 antibody
      see all

    Images

    • Anti-KRTHB3 antibody [EPR12333-112] (ab175217) at 1/10000 dilution + Human skin lysate at 10 µg

      Predicted band size: 54 kDa

    References

    ab175217 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab175217.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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