L-AP4 (mM/ml), group III mGlu agonist (ab144481)
Key features and details
- Selective group III mGlu agonist. 1 ml water soluble pack.
- CAS Number: 23052-81-5
- Purity: > 99%
- Soluble in 1 ml water to give specified mM/ml concentration
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
L-AP4 (mM/ml), group III mGlu agonist -
Description
Selective group III mGlu agonist. 1 ml water soluble pack. -
Biological description
Selective group III mGlu agonist.
Soluble in 1 ml water to give specified mM/ml concentration. Find out more. -
Purity
> 99% -
CAS Number
23052-81-5 -
Chemical structure
Properties
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Chemical name
L-(+)-2-Amino-4-phosphonobutyric acid -
Molecular weight
183.10 -
Molecular formula
C4H10NO5P -
PubChem identifier
179394 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in 1 ml water to give specified mM/ml concentration -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Add 1 ml of water to get an exact ready to use concentration.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
N[C@@H](CCP(=O)(O)O)C(=O)O -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (13)
ab144481 has been referenced in 13 publications.
- Buldyrev I & Taylor WR Inhibitory mechanisms that generate centre and surround properties in ON and OFF brisk-sustained ganglion cells in the rabbit retina. J Physiol 591:303-25 (2013). PubMed: 23045347
- Kalinichev M et al. ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization. J Pharmacol Exp Ther 344:624-36 (2013). PubMed: 23257312
- Goudet C et al. A novel selective metabotropic glutamate receptor 4 agonist reveals new possibilities for developing subtype selective ligands with therapeutic potential. FASEB J 26:1682-93 (2012). PubMed: 22223752
- Klyuch BP et al. Deletion of ecto-5'-nucleotidase (CD73) reveals direct action potential-dependent adenosine release. J Neurosci 32:3842-7 (2012). PubMed: 22423104
- Gosnell HB et al. mGluR8 modulates excitatory transmission in the bed nucleus of the stria terminalis in a stress-dependent manner. Neuropsychopharmacology 36:1599-607 (2011). PubMed: 21451497