Anti-LPA-3 antibody (ab137497)
Key features and details
- Rabbit polyclonal to LPA-3
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-LPA-3 antibody
See all LPA-3 primary antibodies -
Description
Rabbit polyclonal to LPA-3 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human LPA-3 aa 165-259 (internal sequence).
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Positive control
- NT2D1 and PC3 whole cell lysates; Human testis tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab137497 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 40 kDa.
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IHC-P |
1/100 - 1/1000.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 40 kDa. |
IHC-P
1/100 - 1/1000. |
Target
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Function
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins. -
Tissue specificity
Most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 23566 Human
- Omim: 605106 Human
- SwissProt: Q9UBY5 Human
- Unigene: 674915 Human
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Alternative names
- Calcium mobilizing lysophosphatidic acid receptor LP A3 antibody
- Calcium mobilizing lysophosphatidic acid receptor LPA 3 antibody
- Calcium mobilizing lysophosphatidic acid receptor LPA3 antibody
see all
Images
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All lanes : Anti-LPA-3 antibody (ab137497) at 1/1000 dilution
Lane 1 : NT2D1 whole cell lysate
Lane 2 : PC3 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 40 kDa
10% SDS PAGE -
Immunohistochemical analysis of paraffin-embedded Human testis tissue, labelling LPA-3 with ab137497 at 20 µg/ml.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab137497 has not yet been referenced specifically in any publications.