MMP-9 inhibitor (ab142180)
Key features and details
- MMP-9 inhibitor
- CAS Number: 1177749-58-4
- Purity: > 95%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
MMP-9 inhibitor -
Biological description
MMP-9 inhibitor. Role in tumor cell migration, invasion and angiogenesis -
Purity
> 95% -
General notes
This product is manufactured by BioVision, an Abcam company and was previously called 1981 MMP-9 Inhibitor. 1981-500 is the same size as the 500 µg size of ab142180.
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CAS Number
1177749-58-4 -
Chemical structure
Properties
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Chemical name
2-(N-Benzyl-4-methoxyphenylsulfonamido)-5-((diethylamino)methyl)-N-hydroxy-3-methylbenzamide -
Molecular weight
511.63 -
Molecular formula
C27H33N3O5S -
PubChem identifier
21310926 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCN(CC)CC1=CC(=C(C(=C1)C(=O)NO)N(CC2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)OC)C -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (17)
ab142180 has been referenced in 17 publications.
- Tsukamoto S et al. Matrix Metalloproteinase 9 Induced in Esophageal Squamous Cell Carcinoma Cells via Close Contact with Tumor-Associated Macrophages Contributes to Cancer Progression and Poor Prognosis. Cancers (Basel) 15:N/A (2023). PubMed: 37296952
- Bzioueche H et al. Ceramide AD™ Restores Skin Integrity and Function following Exposure to House Dust Mite. Int J Mol Sci 24:N/A (2023). PubMed: 37298186
- Jouida A et al. Exosomes from EGFR-Mutated Adenocarcinoma Induce a Hybrid EMT and MMP9-Dependant Tumor Invasion. Cancers (Basel) 14:N/A (2022). PubMed: 35954442
- Zhang D et al. Crocin alleviates lipopolysaccharide-induced acute respiratory distress syndrome by protecting against glycocalyx damage and suppressing inflammatory signaling pathways. Inflamm Res 69:267-278 (2020). PubMed: 31925528
- Boukhedouni N et al. Type-1 cytokines regulate MMP-9 production and E-cadherin disruption to promote melanocyte loss in vitiligo. JCI Insight 5:N/A (2020). PubMed: 32369451